Ontology highlight
ABSTRACT:
SUBMITTER: Malaguti G
PROVIDER: S-EPMC7946427 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
eLife 20210217
Living cells often need to measure chemical concentrations that vary in time, yet how accurately they can do so is poorly understood. Here, we present a theory that fully specifies, without any adjustable parameters, the optimal design of a canonical sensing system in terms of two elementary design principles: (1) there exists an optimal integration time, which is determined by the input statistics and the number of receptors; and (2) in the optimally designed system, the number of independent c ...[more]