Gait speed, survival, and recommended treatment intensity in older adults with blood cancer requiring treatment.

ABSTRACT:

Background

Brief measures of physical function such as gait speed may be useful to optimize treatment intensity for older adults who have blood cancer; however, little is known about whether such assessments are already captured within oncologists' "gestalt" assessments.

Methods

Gait speed was assessed in 782 patients ≥75 years of age who had blood cancer, with results reported to providers after treatment decisions were made; 408 patients required treatment when different intensities were available per National Comprehensive Cancer Network (NCCN) guidelines. We performed structured abstractions of treatment intensity recommendations into standard intensity, reduced intensity, or supportive care, based on NCCN guidelines. We modeled gait speed and survival using Cox regressi

SUBMITTER: Hantel A 

PROVIDER: S-EPMC7946649 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature