Prenatal exposure to phthalates and maternal metabolic outcomes in a high-risk pregnant Latina population.

ABSTRACT:

Background

Phthalates are a group of endocrine disrupting chemicals that are heavily used throughout industry in flexible plastic and personal-care products. As a result, detectable levels of their metabolites are readily found in humans. Some studies have shown associations of phthalates with diabetes, but associations with gestational diabetes mellitus (GDM) are less clear.

Objective

To investigate the association of 11 prenatal urinary phthalate metabolites and development of GDM, impaired glucose tolerance (IGT), continuous plasma glucose level, and excessive gestational weight gain (GWG) in a population of pregnant Latina women (N = 415) enrolled in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) cohort study.

Methods

Phthalate

SUBMITTER: Zukin H 

PROVIDER: S-EPMC7946766 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature