Neurodegenerative disease is associated with increased incidence of epilepsy: a population based study of older adults.

ABSTRACT:

Objective

To determine the incidence of epilepsy among Medicare beneficiaries with a new diagnosis of Alzheimer dementia (AD) or Parkinson disease (PD).

Methods

Retrospective cohort study of Medicare beneficiaries with an incident diagnosis of AD or PD in the year 2009. The 5-year incidence of epilepsy was examined by sociodemographic characteristics, comorbidities and neurodegenerative disease status. Cox regression models examined the association of neurodegenerative disease with incident epilepsy, adjusting for demographic characteristics and medical comorbidities.

Results

We identified 178,593 individuals with incident AD and 104,157 individuals with incident PD among 34,054,293 Medicare beneficiaries with complete data in 2009. Epilepsy was diagnosed in 4.45% (7,

SUBMITTER: Blank LJ 

PROVIDER: S-EPMC7946790 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature