Influence of Gender in Advanced Heart Failure Therapies and Outcome Following Transplantation.

ABSTRACT: Biological differences between males and females change the course of different diseases and affect therapeutic measures' responses. Heart failure is not an exception to these differences. Women account for a minority of patients on the waiting list for heart transplantation or other advanced heart failure therapies. The reason for this under-representation is unknown. Men have a worse cardiovascular risk profile and suffer more often from ischemic heart disease. Conversely, transplanted women are younger and more frequently have non-ischemic cardiac disorders. Women's poorer survival on the waiting list for heart transplantation has been previously described, but this trend has been corrected in recent years. The use of ventricular assist devices in women is progressively increasing, with

SUBMITTER: Garcia-Cosio MD 

PROVIDER: S-EPMC7946818 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature