Association Between Statins and Cancer Incidence in Diabetes: a Cohort Study of Japanese Patients with Type 2 Diabetes.

ABSTRACT:

Background

The antitumor effect of statins has been highlighted, but clinical study results remain inconclusive. While patients with diabetes are at high risk of cancer, it is uncertain whether statins are effective for cancer chemoprevention in this population.

Objective

This study evaluated the association between statins and cancer incidence/mortality in patients with type 2 diabetes.

Design

This study was a follow-up observational study of the Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes (JPAD) trial, which was a randomized controlled trial of low-dose aspirin in Japanese patients with type 2 diabetes.

Participants

This study enrolled 2536 patients with type 2 diabetes, age 30-85 years, and no history of atherosclerotic cardiovas

SUBMITTER: Okada S 

PROVIDER: S-EPMC7947140 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature