Lung Cancer Attributed Mortality Among 316,336 Early Stage Breast Cancer Cases Treated by Radiotherapy and/or Chemotherapy, 2000-2015: Evidence From the SEER Database.

ABSTRACT:

Objective

To estimate the risk of death from lung cancer in patients treated for breast cancer (BC) in relation to the general population.

Methods

BC data, covering 2000 to 2015, were extracted from the Surveillance, Epidemiology and End Results-18 (SEER-18) cancer registry database. A comparison of lung cancer attributed mortality between BC patients and the general population was performed using standardized mortality ratios (SMRs) and SMRs conditional on survival length (cSMRs). Prognostic factors of lung cancer mortality were identified using flexible parametric modelling. Our model adjusts the effect of downstream (histopathological BC tumor grade and hormone receptor status) and upstream (age at diagnosis, ethnicity, and marital status) factors.

Results

The medi

SUBMITTER: Abera SF 

PROVIDER: S-EPMC7947230 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature