A large real-world cohort study of examined lymph node standards for adequate nodal staging in early non-small cell lung cancer.

ABSTRACT:

Background

The current National Comprehensive Cancer Network (NCCN) guidelines for non-small cell lung cancer (NSCLC) recommend that surgeons sample is not clear. We aimed to define a minimal number of examined lymph nodes for removal or sampling for optimized nodal staging recommendation, with a focus on T_1-3N₀M₀ patients.

Methods

A total of 55,101 consecutive patients were selected, including 52,099 patients with US Surveillance, Epidemiology, and End Results (SEER) data and 3,002 patients in a Chinese multicenter database from 11 thoracic referral centers, who underwent complete resection plus lymph node dissection or sampling for stage T_1-3N₀M₀ NSCLC. Propensity score-matching analysis was performed with R

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC7947406 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature