Machine learning-assisted decision-support models to better predict patients with calculous pyonephrosis.

ABSTRACT:

Background

To develop a machine learning (ML)-assisted model capable of accurately identifying patients with calculous pyonephrosis before making treatment decisions by integrating multiple clinical characteristics.

Methods

We retrospectively collected data from patients with obstructed hydronephrosis who underwent retrograde ureteral stent insertion, percutaneous nephrostomy (PCN), or percutaneous nephrolithotomy (PCNL). The study cohort was divided into training and testing datasets in a 70:30 ratio for further analysis. We developed 5 ML-assisted models from 22 clinical features using logistic regression (LR), LR optimized by least absolute shrinkage and selection operator (Lasso) regularization (Lasso-LR), support vector machine (SVM), extreme gradient boosting (XGBoost)

SUBMITTER: Liu H 

PROVIDER: S-EPMC7947454 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature