B-type natriuretic peptide as a surrogate marker for survival in patients undergoing cardiac surgery.

ABSTRACT:

Background

B-type natriuretic peptide (BNP) is a biomarker predicting morbidity and mortality in patients with congestive heart failure. However, the usefulness of pre- or postoperative BNP levels in patients undergoing cardiac surgery remains uncertain. We sought to determine the association of pre- or postoperative BNP levels on mortality in patients undergoing cardiac surgery under cardiopulmonary bypass (CPB).

Methods

This study retrospectively evaluated 1,642 patients undergoing cardiac surgery under CPB over 2 years. The primary outcomes were 30-day and overall mortality after cardiac surgery.

Results

The 30-day mortality rate was 3.0% (n=49), and the overall mortality occurred in 118 patients during the mean follow-up period of 24.9±8.9 months. In multivariable

SUBMITTER: Lim JY 

PROVIDER: S-EPMC7947500 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature