Increased glucose variability is associated with major adverse events in patients with infective endocarditis undergo surgical treatment.

ABSTRACT:

Background

This study aimed to investigate the prognostic value of glucose variability (GV) in predicting postoperative major adverse events (MAEs) in patients with infective endocarditis (IE) who underwent surgical treatment.

Methods

This retrospective observational study included a total of 381 consecutive patients who underwent surgical treatment in our institution from October 2007 to August 2019. The MAEs included all-cause death, stroke, myocardial infarction, acute heart failure, IE recurrence, acute renal failure and sepsis. Postoperative GV in the first 24 hours was measured by the mean 24-hour glucose, standard deviation, coefficient of variation (CV) and mean amplitude of glycemic excursions. Univariate and multivariate logistic regression analyses were performed

SUBMITTER: Liang M 

PROVIDER: S-EPMC7947509 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature