Patients with asthma or chronic obstructive pulmonary disease (COPD) can generate sufficient inspiratory flows via Easyhaler^® dry powder inhaler: a pooled analysis of two randomized controlled trials.

ABSTRACT:

Background

To evaluate whether patients of varying ages and lung function with asthma or those with chronic obstructive pulmonary disease (COPD) can achieve sufficient inspiratory flows for effective use of the fixed-dose combination of salmeterol-fluticasone propionate and budesonide-formoterol dispensed with the Easyhaler^® (EH) device-metered, multi-dose dry powder inhaler (DPI).

Methods

A pooled analysis of two randomized, multicenter, crossover, open-label studies (NCT01424137; NCT009849061) was conducted to characterize inspiratory flow parameters across the EH, Seretide Diskus (DI) and Symbicort Turbuhaler (TH) inhalers in patients with asthma and/or COPD of varying severity. The primary endpoint was peak inspiratory flow (PIF) rate through the EH.

Result

SUBMITTER: Malmberg LP 

PROVIDER: S-EPMC7947512 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature