Clinical impact of forced vital capacity on exercise performance in patients with chronic obstructive pulmonary disease.

ABSTRACT:

Background

Forced vital capacity (FVC) has been suggested to be a good biomarker for decreased exercise performance in patients with chronic obstructive pulmonary disease (COPD). However, as FVC is highly correlated with forced expiratory volume in 1 second (FEV₁), the relationship between FVC and exercise capacity should be assessed within the category of FEV1, i.e., COPD severity. However, this was not considered in previous studies. Thus, limited data are available on the association between reduced FVC and exercise capacity measured by 6-min walk distance (6MWD) based on COPD severity.

Methods

We performed a cross-sectional study using data from the Korean COPD Subgroup Study (KOCOSS) cohort. We evaluated 1,386 patients with moderate (n=895) and severe-to-very

SUBMITTER: Moon SM 

PROVIDER: S-EPMC7947547 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature