Genome Duplication Increases Meiotic Recombination Frequency: A Saccharomyces cerevisiae Model.

ABSTRACT: Genetic recombination characterized by reciprocal exchange of genes on paired homologous chromosomes is the most prominent event in meiosis of almost all sexually reproductive organisms. It contributes to genome stability by ensuring the balanced segregation of paired homologs in meiosis, and it is also the major driving factor in generating genetic variation for natural and artificial selection. Meiotic recombination is subjected to the control of a highly stringent and complex regulating process and meiotic recombination frequency (MRF) may be affected by biological and abiotic factors such as sex, gene density, nucleotide content, and chemical/temperature treatments, having motivated tremendous researches for artificially manipulating MRF. Whether genome polyploidization would lead to a

SUBMITTER: Fang O 

PROVIDER: S-EPMC7947769 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature