Association of Age With Likelihood of Developing Symptoms and Critical Disease Among Close Contacts Exposed to Patients With Confirmed SARS-CoV-2 Infection in Italy.

ABSTRACT:

Importance

Solid estimates of the risk of developing symptoms and of progressing to critical disease in individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are key to interpreting coronavirus disease 2019 (COVID-19) dynamics, identifying the settings and the segments of the population where transmission is more likely to remain undetected, and defining effective control strategies.

Objective

To estimate the association of age with the likelihood of developing symptoms and the association of age with the likelihood of progressing to critical illness after SARS-CoV-2 infection.

Design, setting, and participants

This cohort study analyzed quarantined case contacts, identified between February 20 and April 16, 2020, in the Lombardy regio

SUBMITTER: Poletti P 

PROVIDER: S-EPMC7948061 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature