A Nonlinear Relation Between Maternal Red Blood Cell Manganese Concentrations and Child Blood Pressure at Age 6-12 y: A Prospective Birth Cohort Study.

ABSTRACT:

Background

Although manganese (Mn) is an essential trace element and a common component of most multivitamins on the market, an adverse effect on blood pressure (BP) has been reported in adults. In addition, the longitudinal relation between prenatal Mn status and childhood BP is still unknown.

Objective

This study investigated the association between prenatal Mn concentrations and risk of elevated BP at ages 3-12 y.

Method

The analyses included 1268 mother-child dyads who were enrolled at birth and followed prospectively at the Boston Medical Center. Maternal RBC Mn concentrations were measured by inductively coupled plasma mass spectrometry, using RBCs collected within 1-3 d after delivery (reflecting late-pregnancy Mn exposure). Child elevated BP was defined as sys

SUBMITTER: Wang G 

PROVIDER: S-EPMC7948198 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature