Impact of previous exposure to systemic corticosteroids on unfavorable outcome in patients hospitalized for COVID-19.

ABSTRACT:

Background

The impact of prior exposure to systemic corticosteroids on COVID-19 severity in patients hospitalized for a SARS-CoV-2 pneumonia is not known. The present study was designed to answer to this question.

Methods

The population study was the Covid-Clinic-Toul cohort which records data about all hospitalized patients with a positive reverse transcriptase polymerase chain reaction for a SARS-CoV-2 infection at Toulouse University hospital, France. Exposure to systemic corticosteroids was assessed at hospital admission. A propensity score (PS) according to corticosteroid exposure was calculated including comorbidities, clinical, radiological and biological variables that impact COVID-19 severity. The primary outcome was composite, including admission to intensive care

SUBMITTER: Lafaurie M 

PROVIDER: S-EPMC7948656 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature