Long-term dietary intake from infancy to late adolescence is associated with gut microbiota composition in young adulthood.

ABSTRACT:

Background

Gut microbiota composition as influenced by long-term diet may be associated with the risk of adult chronic diseases. Thus, establishing the relation of long-term diet, particularly starting from early life, with adult microbiota composition would be an important research advance.

Objective

We aimed to investigate the association of long-term intake of energy, carbohydrate, fiber, protein, and fat from infancy to late adolescence with microbiota composition in adulthood.

Methods

Within the prospective DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study, we sampled stool 1 or 2 times within 1 y from 128 adults (median age: 29 y). Microbiota composition was profiled by 16S ribosomal RNA sequencing. Annual dietary records from age 1

SUBMITTER: Oluwagbemigun K 

PROVIDER: S-EPMC7948843 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature