Risk factors for severe opioid-induced respiratory depression in hospitalized adults: A case-control study.

ABSTRACT: Background: Opioids are commonly prescribed to hospitalized adults to promote adequate pain relief, yet they can cause potentially fatal respiratory depression. Aim: The aim of this study was to examine the risk factors for the development of severe opioid-induced respiratory depression (OIRD) in hospitalized adults to ensure adequate monitoring of high-risk patients. Methods: A retrospective case-control study was conducted using data from the medical records of a university-affiliated hospital in Canada. Cases were eligible if they were adults (≥18 years old) and received opioid analgesia within 24 h of naloxone administration for respiratory depression. Controls had the same eligibility criteria, except for respiratory depression and naloxone administration. The cas

SUBMITTER: Boitor M 

PROVIDER: S-EPMC7951145 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature