Muscle endurance deficits in myositis patients despite normal manual muscle testing scores.

ABSTRACT:

Introduction

It is unclear whether quantitating muscle endurance adds nonredundant information useful for the care of patients with muscular disease.

Methods

Records were retrospectively reviewed for all Johns Hopkins Myositis Center patients with a muscle endurance assessment (n = 128, 226 patient-visits). Muscle endurance and strength were quantitated with the Myositis Functional Index-2 (FI2) and manual muscle testing (MMT), respectively.

Results

Composite FI2 muscle endurance scores were comparable in inclusion body myositis (n = 58), dermatomyositis (n = 31), and polymyositis (n = 39). Overall, muscle endurance correlated with and evolved similarly to strength, inversely to serum creatine kinase. However, in patients with normal or near-normal strength (mean MMT 

SUBMITTER: Amici DR 

PROVIDER: S-EPMC7951326 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature