The Functional Reorganization of Language Network Modules in Glioma Patients: New Insights From Resting State fMRI Study.

ABSTRACT:

Background

Prior investigations of language functions have focused on the response profiles of particular brain regions. However, the specialized and static view of language processing does not explain numerous observations of functional recovery following brain surgery. To investigate the dynamic alterations of functional connectivity (FC) within language network (LN) in glioma patients, we explored a new flexible model based on the neuroscientific hypothesis of core-periphery organization in LN.

Methods

Group-level LN mapping was determined from 109 glioma patients and forty-two healthy controls (HCs) using independent component analysis (ICA). FC and mean network connectivity (mNC: l/rFCw, FCb, and FCg) were compared between patients and HCs. Correlations between mNC and

SUBMITTER: Jin L 

PROVIDER: S-EPMC7953055 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature