Ca²⁺ Complexation With Relevant Bioligands in Aqueous Solution: A Speciation Study With Implications for Biological Fluids.

ABSTRACT: A speciation study on the interaction between Ca²⁺ and ligands of biological interest in aqueous solution is reported. The ligands under study are l-cysteine (Cys), d-penicillamine (PSH), reduced glutathione (GSH), and oxidized glutathione (GSSG). From the elaboration of the potentiometric experimental data the most likely speciation patterns obtained are characterized by only protonated species with a 1:1 metal to ligand ratio. In detail, two species, CaLH₂ and CaLH, for systems containing Cys, PSH, and GSH, and five species, CaLH₅, CaLH₄, CaLH₃, CaLH₂, and CaLH, for system containing GSSG, were observed. The potentiometric titrations were performed at different temper

SUBMITTER: Aiello D 

PROVIDER: S-EPMC7953420 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature