ITRAQ-based proteomics analysis on insomnia rats treated with Mongolian medical warm acupuncture.

ABSTRACT:

Objective

To explore the proteomic changes in the hypothalamus of rats treated with Mongolian medical warm acupuncture for insomnia therapy based proteomics.

Method

We used an iTRAQ-based quantitative proteomic approach to identify proteins that potential molecular mechanisms involved in the treatment of insomnia by Mongolian medical warm acupuncture.

Result

In total, 7477 proteins were identified, of which 36 proteins showed increased levels and 45 proteins showed decreased levels in insomnia model group (M) compared with healthy control group (C), 72 proteins showed increased levels and 44 proteins showed decreased levels from the warm acupuncture treated insomnia group (W) compared with healthy controls (C), 28 proteins showed increased levels and 17 proteins showe

SUBMITTER: Xu Y 

PROVIDER: S-EPMC7953503 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature