MiR-21: a non-specific biomarker of all maladies.
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ABSTRACT:
SUBMITTER: Jenike AE
PROVIDER: S-EPMC7953557 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
miR-21: a non-specific biomarker of all maladies.
Jenike Ana E AE Halushka Marc K MK
Biomarker research 20210312 1
miRNA-21 is among the most abundant and highly conserved microRNAs (miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory roles in health and disease. It is also frequently claimed to be a biomarker of diseases such as cancer and heart disease in bodily-fluid based miRNA studies. Here we dissociate its contributions to cellular physiology and pathology from its potential as a biomarker. We show how it has been claimed as a specific predictive or prognost ...[more]
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