A Risk Score to Predict Clostridioides difficile Infection.

ABSTRACT:

Background

Clostridioides difficile infection (CDI) is a major cause of severe diarrhea. In this retrospective study, we identified CDI risk factors by comparing demographic and clinical characteristics for Kaiser Permanente Northern California members ≥18 years old with and without laboratory-confirmed incident CDI.

Methods

We included these risk factors in logistic regression models to develop 2 risk scores that predict future CDI after an Index Date for Risk Score Assessment (IDRSA), marking the beginning of a period for which we estimated CDI risk.

Results

During May 2011 to July 2014, we included 9986 CDI cases and 2 230 354 members without CDI. The CDI cases tended to be older, female, white race, and have more hospitalizations, emergency department and o

SUBMITTER: Aukes L 

PROVIDER: S-EPMC7953654 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature