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Efficient bioconversion of raspberry ketone in Escherichia coli using fatty acids feedstocks.


ABSTRACT:

Background

Phenylpropanoid including raspberry ketone, is a kind of important natural plant product and widely used in pharmaceuticals, chemicals, cosmetics, and healthcare products. Bioproduction of phenylpropanoid in Escherichia coli and other microbial cell factories is an attractive approach considering the low phenylpropanoid contents in plants. However, it is usually difficult to produce high titer phenylpropanoid production when fermentation using glucose as carbon source. Developing novel bioprocess using alternative sources might provide a solution to this problem. In this study, typical phenylpropanoid raspberry ketone was used as the target product to develop a biosynthesis pathway for phenylpropanoid production from fatty acids, a promising alternative low-cost feedstoc

SUBMITTER: Chang C 

PROVIDER: S-EPMC7953670 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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