Genetic and molecular biology of autism spectrum disorder among Middle East population: a review.

ABSTRACT:

Background

Autism spectrum disorder (ASD) is a neurodevelopmental disease, characterized by impaired social communication, executive dysfunction, and abnormal perceptual processing. It is more frequent among males. All of these clinical manifestations are associated with atypical neural development. Various genetic and environmental risk factors are involved in the etiology of autism. Genetic assessment is essential for the early detection and intervention which can improve social communications and reduce abnormal behaviors. Although, there is a noticeable ASD incidence in Middle East countries, there is still a lack of knowledge about the genetic and molecular biology of ASD among this population to introduce efficient diagnostic and prognostic methods.

Main body

In the pr

SUBMITTER: Rahmani Z 

PROVIDER: S-EPMC7953769 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature