Short-term weight change and live birth among women with unexplained infertility and polycystic ovary syndrome undergoing ovulation induction.

ABSTRACT:

Objective

To determine if short-term weight change among women with unexplained infertility (UI) and polycystic ovary syndrome (PCOS) undergoing ovulation induction is associated with live birth.

Design

Secondary analysis of randomized trials.

Setting

Multicenter fertility trial sites.

Patient(s)

A total of 900 women with UI and 750 women with PCOS.

Main outcome measure(s)

Live birth.

Intervention(s)

Weight assessment at enrollment and start of up to 4-5 cycles of clomiphene, letrozole, or gonadotropins and intrauterine insemination for women with UI and clomiphene or letrozole with regular intercourse for women with PCOS.

Result(s)

Weight data were available for 856 women with UI and 697 women with PCOS. Mean weight change was -0.2 ± 0.3 k

SUBMITTER: Vitek W 

PROVIDER: S-EPMC7953832 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature