Hepatitis C virus infection among people who inject drugs in Bangkok, Thailand, 2005-2010.

ABSTRACT:

Background

Approximately 1% of adults in Thailand are infected with hepatitis C virus (HCV). New direct-acting antiviral agents achieve sustained virologic responses in >95% of HCV-infected patients and are becoming available in countries around the world. To prepare for new HCV treatment options in Thailand, this study characterized HCV infections among people who inject drugs (PWID) in Bangkok.

Methods

The Bangkok Tenofovir Study (BTS) was a pre-exposure prophylaxis trial conducted among PWID, 2005-2013. Blood specimens were randomly selected from PWID screened for the BTS, to test for anti-HCV antibody and HCV RNA. The HVR1 region was amplified by polymerase chain reaction, using multiplex primer sets with unique identifier sequences; amplification products were pooled in

SUBMITTER: Martin M 

PROVIDER: S-EPMC7954142 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature