Progression of electrocardiogram changes in an untreated fabry disease: a case report.

ABSTRACT:

Background

Fabry disease (FD) is a rare lysosomal storage disorder with multiorgan manifestation and associated with an increased morbidity and mortality. Fabry cardiomyopathy includes left ventricular 'hypertrophy' (LVH), cardiac arrhythmias, and heart failure. We report a case of an untreated FD with characteristic findings in electrocardiogram (ECG) over a follow-up period of 10 years.

Case summary

A 53-year-old man with FD presented to our outpatient department. He suffered from symptomatic ventricular extrasystoles. Echocardiography detected LVH and reduced global longitudinal strain. Twelve years ago, first examination was conducted due to ventricular arrhythmias. Electrocardiogram showed a short PQ minus P-wave (P_endQ) interval and negative T-waves. Over ti

SUBMITTER: Mattig I 

PROVIDER: S-EPMC7954241 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature