A new approach to the treatment of advanced heart failure: a case report.

ABSTRACT:

Background

Autonomic imbalance characterized by sympathetic predominance and decreased parasympathetic transmission is a classic feature of heart failure (HF) with reduced left ventricular ejection fraction, leading to disease progression, exercise intolerance, ventricular remodelling, arrhythmias, and premature death. The underlying mechanisms to these processes are not yet fully understood, but the current treatments influence this dysregulation, towards an inhibition of sympathetic hyperactivation. New therapies, such as the stimulation of carotid baroreceptors, enhance this inhibition to restore autonomic balance and to be able to cope with these mechanisms.

Case summary

We report the case of a 76-year-old male with advanced HF at an advanced stage, refractory to optimal

SUBMITTER: Robles-Mezcua A 

PROVIDER: S-EPMC7954250 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature