Association between dementia and systemic rheumatic disease: A nationwide population-based study.

ABSTRACT:

Objectives

Systemic rheumatic disease is characterized by autoimmunity and systemic inflammation and affects multiple organs. Few studies have investigated whether autoimmune diseases increase the risk of dementia. Herein, we evaluate the relationship between systemic rheumatic disease and dementia through a population-based study using the Korean National Health Insurance Service (NHIS) claims database.

Methods

We conducted a nationwide population-based study using the Korean NHIS database, consisting of individuals who submitted medical claims from 2002-2013. Dementia was defined as having an acetylcholinesterase inhibitors (AChEIs) prescription along with symptoms satisfying the Alzhemier's disease (AD) International Classification of Diseases (ICD)-10 codes (F00 or G30),

SUBMITTER: Park H 

PROVIDER: S-EPMC7954284 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature