Revised estimates of leprosy disability weights for assessing the global burden of disease: A systematic review and individual patient data meta-analysis.

ABSTRACT:

Background

Leprosy is a chronic bacterial infection caused by Mycobacterium leprae, which may lead to physical disability, stigma, and discrimination. The chronicity of the disease and disabilities are the prime contributors to the disease burden of leprosy. The current figures of the disease burden in the 2017 global burden of disease study, however, are considered to be under-estimated. In this study, we aimed to systematically review the literature and perform individual patient data meta-analysis to estimate new disability weights for leprosy, using Health-Related Quality of Life (HRQOL) data.

Methodology/principal findings

The search strategy included all major databases with no restriction on language, setting, study design, or year of publication. Studies on human pop

SUBMITTER: Nanjan Chandran SL 

PROVIDER: S-EPMC7954345 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature