Possible Role of Regulatory B Cells in Different Behcet's Disease Phenotypes and Therapies: First Report from Egypt.

ABSTRACT:

Background and aim

The data about the role of regulatory B cells (Breg) in Behcet Disease (BD) are scarce. We aimed to evaluate the frequency of total B lymphocytes and Breg cells in different BD phenotypes and therapies attempting to unravel their function.

Methods

This cross-sectional study included 35 BD patients and 39 healthy controls (HCs). The demographic data of the study subjects were collected including age and gender. Current medications including disease-modifying anti-rheumatic drugs (DMARDs) were recorded. All patients underwent testing for baseline laboratory investigations including full blood count, liver and kidney function tests, erythrocyte sedimentation rate (ESR) by Westergren blot and C-reactive protein (CRP). Measurement of the total B lymphocytes and

SUBMITTER: Hetta HF 

PROVIDER: S-EPMC7955029 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature