Early Aspirin Discontinuation After Coronary Stenting: A Systematic Review and Meta-Analysis.

ABSTRACT: Background The clinical impact of early aspirin discontinuation compared with dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary intervention with stenting remains poorly studied. We investigated the clinical outcomes of patients assigned to either early aspirin discontinuation or DAPT after percutaneous coronary intervention with stenting. Methods and Results We performed a meta-analysis of aggregate data from randomized clinical trials enrolling participants receiving a percutaneous coronary intervention with stenting and assigned to either early aspirin discontinuation or DAPT. Scientific databases were searched from inception through March 30, 2020. Trial-level hazard ratios (HRs) and 95% CIs were pooled using a random effects model with inverse variance weig

SUBMITTER: Wiebe J 

PROVIDER: S-EPMC7955304 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature