Risk Factor Burden and Long-Term Prognosis of Patients With Premature Coronary Artery Disease.

ABSTRACT: Background Coronary artery disease (CAD) is increasing among young adults. We aimed to describe the cardiovascular risk factors and long-term prognosis of premature CAD. Methods and Results Using the Duke Databank for Cardiovascular Disease, we evaluated 3655 patients admitted between 1995 and 2013 with a first diagnosis of obstructive CAD before the age of 50 years. Major adverse cardiovascular events (MACEs), defined as the composite of death, myocardial infarction, stroke, or revascularization, were ascertained for up to 10 years. Cox proportional hazard regression models were used to assess associations with the rate of first recurrent event, and negative binomial log-linear regression was used for rate of multiple event recurrences. Past or current smoking was the most frequent cardio

SUBMITTER: Zeitouni M 

PROVIDER: S-EPMC7955368 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature