Race, Body Mass Index, and the Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.

ABSTRACT: Background Higher body mass index (BMI) is associated with increased risk of incident atrial fibrillation (AF), but it is not known whether this relationship varies by race/ethnicity. Methods and Results Eligible participants (6739) from MESA (Multi-Ethnic Study of Atherosclerosis) were surveilled for incident AF using MESA hospital surveillance, scheduled MESA study ECG, and Medicare claims data. After a median 13.8 years of follow-up, 970 participants (14.4%) had incident AF. With BMI modeled categorically in a Cox proportional hazards model, only those with grade II and grade III obesity had increased risks of AF (hazard ratio [HR], 1.50; 95% CI, 1.14-1.98, P=0.004 for grade II obesity and HR, 2.13; 95% CI, 1.48-3.05, P<0.0001 for grade III obesity). The relationship betwe

SUBMITTER: Singleton MJ 

PROVIDER: S-EPMC7955459 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature