Long-Term PM_2.5 Exposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta-Analysis.

ABSTRACT: Background Fine particulate matter <2.5 µm in diameter (PM_2.5) has known effects on cardiovascular morbidity and mortality. However, no study has quantified and compared the risks of incident myocardial infarction, incident stroke, ischemic heart disease (IHD) mortality, and cerebrovascular mortality in relation to long-term PM_2.5 exposure. Methods and Results We sought to quantitatively summarize studies of long-term PM_2.5 exposure and risk of IHD and stroke events by conducting a review and meta-analysis of studies published by December 31, 2019. The main outcomes were myocardial infarction, stroke, IHD mortality, and cerebrovascular mortality. Random effects meta-analyses were used to estimate the combined risk of each outcome among studies. We reviewed

SUBMITTER: Alexeeff SE 

PROVIDER: S-EPMC7955467 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature