Optical Coherence Tomography Predictors for a Favorable Vascular Response to Statin Therapy.

ABSTRACT: Background Specific plaque phenotypes that predict a favorable response to statin therapy have not been systematically studied. This study aimed to identify optical coherence tomography predictors for a favorable vascular response to statin therapy. Methods and Results Patients who had serial optical coherence tomography imaging at baseline and at 6 months were included. Thin-cap area (defined as an area with fibrous cap thickness <200 μm) was measured using a 3-dimensional computer-aided algorithm, and changes in the thin-cap area at 6 months were calculated. A favorable vascular response was defined as the highest tertile in the degree of reduction of the thin-cap area. Macrophage index was defined as the product of the average macrophage arc and length of the lesion with macrophage infi

SUBMITTER: Nakajima A 

PROVIDER: S-EPMC7955485 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature