Fast computational optimization of TMS coil placement for individualized electric field targeting.

ABSTRACT:

Background

During transcranial magnetic stimulation (TMS) a coil placed on the scalp is used to non-invasively modulate activity of targeted brain networks via a magnetically induced electric field (E-field). Ideally, the E-field induced during TMS is concentrated on a targeted cortical region of interest (ROI). Determination of the coil position and orientation that best achieve this objective presently requires a large computational effort.

Objective

To improve the accuracy of TMS we have developed a fast computational auxiliary dipole method (ADM) for determining the optimum coil position and orientation. The optimum coil placement maximizes the E-field along a predetermined direction or, alternatively, the overall E-field magnitude in the targeted ROI. Furthermore, ADM c

SUBMITTER: Gomez LJ 

PROVIDER: S-EPMC7956218 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature