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ABSTRACT: Objective
To define the association between oral and systemic manifestations of Sjögren syndrome (SS) and quality of life (QOL).Methods
We analyzed a cross-sectional survey conducted by the Sjögren's Foundation in 2016, with 2961 eligible responses. We defined oral symptom and sign exposures as parotid gland swelling, dry mouth, mouth ulcers/sores, oral candidiasis, trouble speaking, choking or dysphagia, sialolithiasis or gland infection, and dental caries. Systemic exposures included interstitial lung disease, purpura/petechiae/cryoglobulinemia, vasculitis, neuropathy, leukopenia, interstitial nephritis, renal tubular acidosis, autoimmune hepatitis, primary biliary cholangitis, or lymphoma. Outcomes included SS-specific QOL questions generated by SS experts and patients.<
SUBMITTER: McCoy SS
PROVIDER: S-EPMC7956920 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature