Upgrading to cardiac resynchronisation therapy: Concordance of real-world experience with clinical guidelines.

ABSTRACT:

Objective

Revision to cardiac resynchronisation therapy (CRT) in patients with existing pacemakers with worsening heart failure (HF) can improve symptoms and cardiac function. We identify factors that predict improvement in left ventricular ejection fraction (LVEF) within a year of CRT revision.

Methods

We performed a retrospective study of 146 consecutive patients (16% female, mean age 73 ± 11 years, mean LVEF 27 ± 8%) undergoing revision to CRT (January 2012 to May 2018) in a single tertiary centre. LVEF was measured pre-revision and 3, 6 and 12 months post-upgrade.

Results

At 6 months, 68% of patients demonstrated improvement in LVEF (mean ΔLVEF + 6.7% ± 9.6). Compared to patients in atrial fibrillation (AF), patients with sinus rhythm had a greater improvement in

SUBMITTER: Tan L 

PROVIDER: S-EPMC7957085 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature