Domains and outcome measures for the assessment of limited cutaneous systemic sclerosis: a scoping review protocol.

ABSTRACT:

Introduction

Limited cutaneous systemic sclerosis (lcSSc) is the most frequent subset of systemic sclerosis. Despite this, lcSSc is not the major focus of clinical studies. The lack of interventional studies in lcSSc is due, in part, to a paucity of relevant outcome measures to effectively evaluate this subset. A combined response index dedicated to lcSSc would facilitate development of well-designed trials and approval of new drugs. The objective of this scoping review is to perform a broad and comprehensive identification of the outcome measures (core set items) within relevant domains, which have been used so far to assess lcSSc.

Methods and analysis

The planned scoping review will be based on the approach proposed by Arksey et al and further developed by Levac

SUBMITTER: Lescoat A 

PROVIDER: S-EPMC7957124 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature