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Emergent robustness of bacterial quorum sensing in fluid flow.


ABSTRACT: Bacteria use intercellular signaling, or quorum sensing (QS), to share information and respond collectively to aspects of their surroundings. The autoinducers that carry this information are exposed to the external environment; consequently, they are affected by factors such as removal through fluid flow, a ubiquitous feature of bacterial habitats ranging from the gut and lungs to lakes and oceans. To understand how QS genetic architectures in cells promote appropriate population-level phenotypes throughout the bacterial life cycle requires knowledge of how these architectures determine the QS response in realistic spatiotemporally varying flow conditions. Here we develop and apply a general theory that identifies and quantifies the conditions required for QS activation in fluid flow by sy

SUBMITTER: Dalwadi MP 

PROVIDER: S-EPMC7958174 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature