Clinical characteristics of severe neonatal enterovirus infection: a systematic review.

ABSTRACT:

Background

Enterovirus (EV) is a common cause of infection in neonates. Neonates are at high risk of enterovirus infection with serious clinical manifestations and high lethality. This review systematically summarized the clinical characteristics of neonates with severe enteroviral infection to provide evidence for the identification and treatment of severe neonatal EV infection.

Methods

PubMed, Embase, and Web of Science were searched for original studies on neonates with severe EV infections from January 1, 2000, to November 27, 2020. Two reviewers independently screened the literature, extracted the data, and performed a descriptive analysis.

Results

In total, 66 articles with 237 cases of severe neonatal enterovirus infection were included. All neonates developed

SUBMITTER: Zhang M 

PROVIDER: S-EPMC7958388 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature