Enhancing magnetic resonance imaging-driven Alzheimer's disease classification performance using generative adversarial learning.

ABSTRACT:

Background

Generative adversarial networks (GAN) can produce images of improved quality but their ability to augment image-based classification is not fully explored. We evaluated if a modified GAN can learn from magnetic resonance imaging (MRI) scans of multiple magnetic field strengths to enhance Alzheimer's disease (AD) classification performance.

Methods

T1-weighted brain MRI scans from 151 participants of the Alzheimer's Disease Neuroimaging Initiative (ADNI), who underwent both 1.5-Tesla (1.5-T) and 3-Tesla imaging at the same time were selected to construct a GAN model. This model was trained along with a three-dimensional fully convolutional network (FCN) using the generated images (3T*) as inputs to predict AD status. Quality of the generated images was evaluated us

SUBMITTER: Zhou X 

PROVIDER: S-EPMC7958452 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature