Relationships between depressive symptoms and brain responses during emotional movie viewing emerge in adolescence.

ABSTRACT: Affective disorders such as major depression are common but serious illnesses characterized by altered processing of emotional information. Although the frequency and severity of depressive symptoms increase dramatically over the course of childhood and adolescence, much of our understanding of their neurobiological bases comes from work characterizing adults' responses to static emotional information. As a consequence, relationships between depressive brain phenotypes and naturalistic emotional processing, as well as the manner in which these associations emerge over the lifespan, remain poorly understood. Here, we apply static and dynamic inter-subject correlation analyses to examine how brain function is associated with clinical and non-clinical depressive symptom severity in 112 childr

SUBMITTER: Gruskin DC 

PROVIDER: S-EPMC7958984 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature