Hypertensive Disorders of Pregnancy and Subsequent Risk of Premature Mortality.

ABSTRACT:

Background

Hypertensive disorders of pregnancy (HDPs) are leading causes of maternal and perinatal morbidity and mortality. However, it is uncertain whether HDPs are associated with long-term risk of premature mortality (before age 70 years).

Objectives

The objective of this study was to evaluate whether HDPs were associated with premature mortality.

Methods

Between 1989 and 2017, the authors followed 88,395 parous female nurses participating in the Nurses' Health Study II. The study focused on gestational hypertension and pre-eclampsia within the term HDPs. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between HDPs and premature mortality were estimated by using Cox proportional hazards models, with adjustment for relevant confounders.

SUBMITTER: Wang YX 

PROVIDER: S-EPMC7959184 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature