Significant amelioration of hepatitis C virus infection in a hyperendemic area: longitudinal evidence from the COMPACT Study in Taiwan.

ABSTRACT:

Objectives

Hepatitis C virus (HCV) infection is the leading cause of cirrhosis and hepatocellular carcinoma worldwide. Tzukuan, located in the southwestern area of Taiwan, is an HCV hyperendemic area (>30%). This study aimed to assess the changing epidemiological characteristics of HCV infection and to evaluate the long-term outcomes after the implementation of public health strategies for two decades.

Design

A population-based retrospective cohort study.

Setting

A comprehensive care programme was implemented, namely COMPACT Study, in Tzukuan since 1997.

Participants

A total of 10 714 residents participated the screening.

Outcome measures

The HCV status, demographic and clinical profiles of the participants were recorded and validated annually from 2000

SUBMITTER: Tsai PC 

PROVIDER: S-EPMC7959235 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature