Transmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing.

ABSTRACT: Following the detection of the first imported case of COVID-19 in the northern sector of Ghana, we molecularly characterized and phylogenetically analysed sequences, including three complete genome sequences, of severe acute respiratory syndrome coronavirus 2 obtained from nine patients in Ghana. We performed high-throughput sequencing on nine samples that were found to have a high concentration of viral RNA. We also assessed the potential impact that long-distance transport of samples to testing centres may have on sequencing results. Here, two samples that were similar in terms of viral RNA concentration but were transported from sites that are over 400 km apart were analyzed. All sequences were compared to previous sequences from Ghana and representative sequences from regions where our

SUBMITTER: Sylverken AA 

PROVIDER: S-EPMC7959303 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature